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Professors » Eduardo Lani Volpe Silveira

Eduardo Lani Volpe da Silveira is an Assistant Professor at University of Sao Paulo, Brazil, in the Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences. Dr. Silveira obtained Masters and PhD degrees in Immunology and had a 6-year postdoctoral period in the same field. His strong background in vaccine development has allowed him to investigate the development of protective immune responses against viral and parasitic infections. Quantification of SIV and HIV Envelope-specific antibody-secreting cells (ASCs) and production of anti-SIV and anti-HIV monoclonal antibodies (mAbs) have been done from rhesus macaque samples to study immune responses derived from viral infections and immunizations. T cell responses were also targeted with description of CD8 and CD4 T cell epitopes and their respective mechanisms of action during viral infection (Lymphocryptovirus) in rhesus macaques and parasitic infection (Trypanosoma cruzi) in mice. Currently, Dr. Silveira research is focused on B cell responses elicited by viral infections (Dengue, Zika, Chikungunya) or immunizations (Dengue, Influenza and Hepatitis B). For this, different B cell subsets have been assessed as well as follicular T helper cells through multiple approaches. Production of flaviviruses-specific mAbs have also been performed to evaluate their therapeutic potential.




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Last update 23/09/2016 às 14h52